PFOS and PFOA Toxicological Overview

 Toxic effects following repeated oral exposure includes effects on the liver, gastrointestinal and thyroid hormone effects  Hepatotoxicity is the main effect reported in animals exposed to PFOS or PFOA via ingestion  A small number of occupational studies have reported an association between exposure to PFOS or PFOA and several forms of cancer.  Animals studies suggest that both PFOS and PFOA may be carcinogenic at relatively high dose levels Animal studies indicate no marked effects on reproductive function nor development at levels below those producing maternal toxicity